Oprd1^tm1Jep

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Species

Mus musculus

Symbol

Oprd1^tm1Jep

Category

allele

Allele of gene

Oprd1

Transgenic Constructs

None

Synonyms

• DOR-1 KO
• DOR-KO

Description

Exon 2 was replaced by a neomycin selection cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice using an antiserum directed against the amino terminal. Furthermore, an absence of ligand binding was determined via autoradiographic analysis of radiolabeled ligands that preferentially bind to the pharmacologically defined receptors, delta1 and delta2.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations