Drd2^tm1Ebo

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Species

Mus musculus

Symbol

Drd2^tm1Ebo

Category

allele

Allele of gene

Drd2

Transgenic Constructs

None

Synonyms

• D2R^-

Description

Exon 2, which contains the translational start codon, was replaced by a neomycin selection cassette inserted by homologous recombination. Transcript was undetected in homozygous mutant mice by Northern blot analysis of RNA isolated from striata. An absence of functional protein was determined by radiolabeled ligand binding analyses.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations