Allele/Variant

Ghrtm1Jjk

Species
Mus musculus
Symbol
Ghrtm1Jjk
Category
allele
Allele of gene
Ghr
Transgenic Constructs
None
Synonyms
  • BH-R-KO
  • GHR-
Description
Exon 4 and 500 bp of downstream intronic sequences were replaced with a neomycin resistance cassette via homologous recombination. Northern blot and RT-PCR analysis of liver mRNA from homozygous mutant animals failed to detect gene expression. Western blot analysis of homozygous mutant liver samples did not detect protein product.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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