Allele/Variant

Plcg1tm1Gcrp

Species
Mus musculus
Symbol
Plcg1tm1Gcrp
Category
allele
Allele of gene
Plcg1
Transgenic Constructs
None
Synonyms
None
Description
Coding sequence was disrupted by the insertion of a neomycin selection cassette. While normal protein was undetected by Western blot analysis of MEFs derived from homozygous mutant mice, low levels of a shortened peptide containing both amino and carboxy termini was. Calcium mobilization assays showed that the mutant protein responded to serum, but not epidermal growth factor.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations