Version: 8.0.0
Date: Tue Jan 28 2025
Top3btm1Jcw
MGI:2388157
Allele of Top3b
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Top3btm1Jcw

Species
Mus musculus
Symbol
Top3btm1Jcw
Category
allele
Allele of gene
Top3b
Transgenic Constructs
None
Synonyms
  • top3beta-/-
Description
A region of the gene spanning nucleotides 777 to 1490 of the coding sequence was replaced with a PGK-neo cassette. This region includes the active site tyrosine 336. Gene expression was undetectable by RT-PCR analysis of liver mRNA from homozygous mutant animals.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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