Lipe^tm1Rze

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Species

Mus musculus

Symbol

Lipe^tm1Rze

Category

allele

Allele of gene

Lipe

Transgenic Constructs

None

Synonyms

• HSL-ko
• HSL^-

Description

A floxed neomycin selection cassette was inserted in intron 1 and an additional loxP site was inserted 3' to exon 7. The resulting targeted ES cells were subjected to transient cre expression. Exons 2 to 7 as well as neomycin selection cassette were deleted. In addition to this allele, transient expression provided recombinant ES cells in which only the selection cassette was deleted. These cells were used to produce Lipe^tm2Rze.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations