Prdm2^tm1Shg

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Species

Mus musculus

Symbol

Prdm2^tm1Shg

Category

allele

Allele of gene

Prdm2

Transgenic Constructs

None

Synonyms

• RIZ1^-

Description

The RIZ1 protein product was disrupted by insertion of a neomycin resistance cassette into the center of the sequence encoding the PR domain in exon 5. The RIZ2 protein product, which begins transcription at exon 6, was not affected by the gene targeting event. Absence of RIZ1 gene expression in homozygous mutant animals was verified by Northern blot of adult mouse brain RNA, Western blot of adult testis proteins, and RT-PCR analysis.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations