Allele/Variant

Drd2tm1Schm

Species
Mus musculus
Symbol
Drd2tm1Schm
Category
allele
Allele of gene
Drd2
Transgenic Constructs
None
Synonyms
  • D2 -
  • D2R-KO
Description
A 3' portion of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the amino terminal extracellular domain, transmembrane spanning domains 1 and 2, and the first intracellular domain. Transcript was undetected by Northern blot analysis of RNA obtained from the dorsal striatum of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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