Allele/Variant

Cox17tm1Kako

Species
Mus musculus
Symbol
Cox17tm1Kako
Category
allele
Allele of gene
Cox17
Transgenic Constructs
None
Synonyms
  • COX17(-)
Description
The majority of exons 1 and 2, as well as the intervening intron, were replaced with a construct containing GFP followed by neo. GFP was inserted immediately downstream of the endogenous start codon. Northern blot analysis of heterozygous mutant mice showed transcript levels to be reduced by approximately 50% in brain, heart, kidney, and skeletal muscle samples.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations