Allele/Variant

Cyp19a1tm1Sih

Species
Mus musculus
Symbol
Cyp19a1tm1Sih
Category
allele
Allele of gene
Cyp19a1
Transgenic Constructs
None
Synonyms
  • ArKO
Description
Sequence encompassing the proximal promoter and exons 1 and 2 was replaced by a neomycin selection inserted by homologous recombination. The deleted region included transcriptional and translational start sites and encoded amino acids essential for transmembrane topology. RT-PCR analysis of ovary and brain tissue indicated an absence of transcript in homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations