Allele/Variant

Gata1tm5(GATA3)Sho

Species
Mus musculus
Symbol
Gata1tm5(GATA3)Sho
Category
allele
Allele of gene
Gata1
Transgenic Constructs
None
Synonyms
  • G1G3ki
Description
Sequence extending from the start codon in exon 2 to the EcoRI site in exon 3 was replaced with a construct containing human GATA3 cDNA sequence followed by a floxed PGK-neo cassette. Northern blot analyses of cell lines derived from mutant embryos indicated that a transcript comprised of both GATA3 and Gata1 sequence was expressed in erythroid cells (but not in myeloid cells). The presence of a protein translated from GATA3 sequence was verified by immunostaining. No Gata1 protein was detected.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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