Allele/Variant

Atf1tm1Gsc

Species
Mus musculus
Symbol
Atf1tm1Gsc
Category
allele
Allele of gene
Atf1
Transgenic Constructs
None
Synonyms
  • ATF1-
Description
Homologous recombination of a construct containing lacZ and neo resulted in the deletion of a portion of exon 3 and all of exons 4 through 7. The targeted region encoded amino acids 200 through 1380, corresponding to the protein kinase A and leucine zipper domains. Protein was undetected in homozygous mutant mice by Western blot analysis of kidney, liver, and testis tissues. Beta-galactosidase staining showed the expression pattern of lacZ to be similar to that of the endogenous gene.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations