Allele/Variant

Tg(GFAP-Hras1)2Agu

Species
Mus musculus
Symbol
Tg(GFAP-Hras1)2Agu
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • GFAP-H-RASG12V
  • GFAP-V12Ha-ras-IRESLacZ
Description
The transgene consists of the human GFAP promoter fused to an Hras1 cDNA, an IRES-lacZ cassette, and a floxed PGK-neo cassette. The human GFAP promoter directs transgene expression in the astrocytes. The Hras1 sequence contains an HA tag at the amino terminus. Western blot analysis of astrocytes from transgenic animals confirmed cell-specific expression of the transgene. Northern blot analysis of brain RNA also confirmed transgene expression.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations