Version: 8.0.0
Date: Tue Jan 28 2025
Tg(LPV-TAg121)2Tvd
MGI:2445949Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(LPV-TAg121)2Tvd

Species
Mus musculus
Symbol
Tg(LPV-TAg121)2Tvd
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • dl1137
  • LST1137
Description
The transgene consists of a lymphotrophic papovavirus (LPV) enhancer/early promoter and a mutant SV40 T antigen sequence truncated after amino acid 121 followed by 11 missense residues. The resulting protein includes the RB1-binding region but lacks the small t antigen and TRP53-binding region. Regulatory sequences direct expression of the transgene in B- and T-lymphocytes and choroid plexus epithelium.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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