Allele/Variant

Tg(Cga-LHB/CGB)94Jhn

Species
Mus musculus
Symbol
Tg(Cga-LHB/CGB)94Jhn
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • LH-CTP
  • LHbeta-CTP
Description
The transgene contains the entire bovine luteinizing hormone beta (LHB) cDNA fused to 87 bp encoding the c-terminal peptide (CTP) of the human chorionic gonadotropin beta subunit (CGB). The bovine glycoprotein hormone alpha subunit (CGA) promoter (positions -315 to +45) was used to drive expression in gonadotropes. Immunohistochemical analysis confirmed both LHB and CTP expression in the pituitaries.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
  • LHB
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations