Allele/Variant

Tg(Prrx1-Hand2)4Eno

Species

Mus musculus

Symbol

Tg(Prrx1-Hand2)4Eno

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

bHLH
Tg(Pr2x1-Hand2)4Eno

Description

The transgene consists of a mouse Prrx1 promoter fused to a mutant Hand2 cDNA deleted for residues 1-90 and 155-217. The mouse Prrx1 promoter was used to drive transgene expression in the forelimb bud and anterior mesoderm of the hindlimb in E10.5 embryos. The Hand2 construct also contains an N-terminal Myc epitope tag and a 3' human growth hormone polyadenylation signal.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Hand2 (Mmu)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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