Allele/Variant

Tg(Prrx1-Hand2)7Eno

Species

Mus musculus

Symbol

Tg(Prrx1-Hand2)7Eno

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

F119P
Tg(Pr2x1-Hand2)7Eno

Description

The transgene consists of a mouse Prrx1 promoter fused to a mutant Hand2 cDNA with a phenylalanine to proline substitution at residue 119 (F119P). The mouse Prrx1 promoter was used to drive transgene expression in the forelimb bud and anterior mesoderm of the hindlimb in E10.5 embryos. The Hand2 construct also contains an N-terminal Myc epitope tag and a 3' human growth hormone polyadenylation signal.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Hand2 (Mmu)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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