Version: 8.0.0
Date: Tue Jan 28 2025
Ltb/Tnf/Ltatm1Dvk
MGI:2446566
Allele of Lta
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ltb/Tnf/Ltatm1Dvk

Species
Mus musculus
Symbol
Ltb/Tnf/Ltatm1Dvk
Category
allele
Allele of gene
Lta
Transgenic Constructs
None
Synonyms
  • TNF/LTDelta3
  • Tnfabc-
Description
An 8.4 kb region, containing the entire Tnf gene and the last coding exons of the Lta and Ltb genes, was deleted by cre mediated recombination of surrounding loxP sites inserted within Lta and Ltb via homologous recombiantion. Partial coding regions of Lta and Ltb were left intact separtated by a single loxP site, however RT-PCR analysis of homozygous mutant splenocytes activated by concanavalin A indicated an absence of transcript from each locus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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