Version: 8.0.0
Date: Tue Jan 28 2025
Ltb/Tnf/Ltatm1Dvk
MGI:2446568
Allele of Ltb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ltb/Tnf/Ltatm1Dvk

Species
Mus musculus
Symbol
Ltb/Tnf/Ltatm1Dvk
Category
allele
Allele of gene
Ltb
Transgenic Constructs
None
Synonyms
  • TNF/LTDelta3
  • Tnfabc-
Description
In an 8.4 kb region, containing the entire Tnf gene and the last coding exons of the Lta and Ltb genes, was deleted by cre mediated excision of sequence between loxP sites inserted within Lta and Ltb via homologous recombination. Partial coding regions of Lta and Ltb were left intact separated by a single loxP site. RT-PCR analysis of homozygous mutant splenocytes activated by concanavalin A indicated an absence of transcript from all three loci.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page