Version: 8.0.0
Date: Tue Jan 28 2025
Tg(PDGFB-PSEN1)1Jhd
MGI:2447324Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(PDGFB-PSEN1)1Jhd

Species
Mus musculus
Symbol
Tg(PDGFB-PSEN1)1Jhd
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • PS1wt
Description
A PDGFB promoter fused to a human PSEN1 cDNA, which includes the intron between exons 4 and 5, was used for the transgene. The PDGFB promoter was used to drive transgene expression in neurons. Transgene expression was confirmed by Northern and Western blot analysis of brain extracts derived from transgenic animals.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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