Allele/Variant

Kcnj3tm1Kwn

Species
Mus musculus
Symbol
Kcnj3tm1Kwn
Category
allele
Allele of gene
Kcnj3
Transgenic Constructs
None
Synonyms
  • GIRK1 KO
  • Kir3.1 knock-out
Description
Exon 3 was deleted by homologous and cre mediated recombination in ES cells. The deleted sequence encoded the pore and transmembrane domains, the entire amino terminus, and the initiator methionine. Normal protein was undetected by Western blot analysis of atrial tissue obtained from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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