Smarcb1^tm3Sho

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Species

Mus musculus

Symbol

Smarcb1^tm3Sho

Category

allele

Allele of gene

Smarcb1

Transgenic Constructs

None

Synonyms

• Snf5^inv

Description

A loxP-flanked neomycin selection cassette was inserted into intron 1 and a single loxP site in the opposite orientation was inserted 0.8 kb upstream of exon 1. The neomycin selection cassette was removed by transient Cre expression in ES cells, leaving oppositely oriented loxP sites flanking exon 1 in the final allele. Upon Cre-mediated recombination, exon 1 and flanking sequences are inverted in orientation with respect to the rest of the gene.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations