Allele/Variant

Stat2tm1Shnd

Species
Mus musculus
Symbol
Stat2tm1Shnd
Category
allele
Allele of gene
Stat2
Transgenic Constructs
None
Synonyms
  • Stat2-/-
Description
The gene was disrupted by replacement of exons 1-4 with a PGK-neo cassette via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of primary mouse embryonic fibroblast (PMEF) extracts prepared from homozygous mutant embryos. Stat1 expression was reduced by 50% in Stat2-deficient cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations