Xdh^tm1Mrc

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Species

Mus musculus

Symbol

Xdh^tm1Mrc

Category

allele

Allele of gene

Xdh

Transgenic Constructs

None

Synonyms

• XOR^-

Description

A self-excising neomycin resistance cassette was inserted into exon 3 of the endogenous gene. The targeting construct was comprised of sequence encoding GFP followed by a floxed region containing a mouse testes-specific Ace promoter fused to the cre recombinase and neomycin resistance genes. The floxed region undergoes self-excision during spermiogenesis, resulting in the production of protein encoded by exons 1 and 2 and a 5' portion of exon 3 fused to GFP.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations