Sall2^tm1Ryn

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Species

Mus musculus

Symbol

Sall2^tm1Ryn

Category

allele

Allele of gene

Sall2

Transgenic Constructs

None

Synonyms

None

Description

The gene was disrupted by replacement of a portion of exon 2 encoding 5 N-terminal zinc fingers with a neomycin resistance cassette via homologous recombination. Northern blot analysis of mRNA from homozygous mutant mice did not detect wild-type transcript. However, hybridization with a C-terminal probe revealed a shortened transcript containing the neo cassette. The mutant transcript contains multiple stop codons as assessed by sequence analysis and most likely does not encode a functional protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations