Version: 8.0.0
Date: Tue Jan 28 2025
Nkx2-5tm2(cre)Rph
MGI:2448972
Allele of Nkx2-5
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nkx2-5tm2(cre)Rph

Species
Mus musculus
Symbol
Nkx2-5tm2(cre)Rph
Category
allele
Allele of gene
Nkx2-5
Transgenic Constructs
Synonyms
  • Nkx2-5IRESCre
  • Nkx2.5-Cre
Description
Sequence encoding cre recombinase adjoined to an IRES was inserted into the 3' UTR of the endogenous locus via homologous recombination. A single frt site remained in the UTR after an frt-flanked hygromycin selection cassette was excised. A lack of observed allele complementation indicated that the inserted sequence did not significantly affect expression of the endogenous locus.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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