Allele/Variant

Unc13atm1Bros

Species
Mus musculus
Symbol
Unc13atm1Bros
Category
allele
Allele of gene
Unc13a
Transgenic Constructs
None
Synonyms
  • Munc13-1-deficient
  • Unc13aKO
Description
The gene was disrupted by the replacement of 4 exons encoding amino acids 494-619 (which includes the C1 domain) with a neomycin resistance cassette via homologous recombination. The null allele was confirmed by Western blot analysis using antibodies directed against the extreme N- and C-termini of the protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations