Version: 8.0.0
Date: Tue Jan 28 2025
Commd10Tg(Vav1-icre)A2Kio
MGI:2449949
Allele of Commd10
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Commd10Tg(Vav1-icre)A2Kio

Species
Mus musculus
Symbol
Commd10Tg(Vav1-icre)A2Kio
Category
allele
Allele of gene
Commd10
Transgenic Constructs
Synonyms
  • Tg(Vav1-cre)1Kio
  • Tg(Vav1-cre)A2Kio
Description
This transgene expresses Cre recombinase under the control of a vav promoter. This promoter was shown to be active in lymph nodes, thymus, spleen, Peyer's patches, intestinal cryptopatches, ovaries and testes. Line A2 inserted into the gene at 47022629-47022630 (Build GRCm38/mm10). The insetion results in a functional knock-out in homozygous mice.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
  • Vav1
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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