Version: 8.0.0
Date: Tue Jan 28 2025
Tg(KRT18-cre/ERT2)1Rgo
MGI:2450291Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(KRT18-cre/ERT2)1Rgo

Species
Mus musculus
Symbol
Tg(KRT18-cre/ERT2)1Rgo
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • K18CreER
  • K18iresCreERT2
Description
The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain inserted into exon 7 of human KRT18. Human KRT18 regulatory sequences were used to drive transgene expression in epithelial cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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