Tec^tm1Welm

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Species

Mus musculus

Symbol

Tec^tm1Welm

Category

allele

Allele of gene

Tec

Transgenic Constructs

None

Synonyms

• Tec^-

Description

The insertion of a neomycin selection cassette disrupted the endogenous allele by replacing exon 2 and surrounding intronic sequence. The deleted exon contained the start codon, encoded 45 residues of the Pleckstrin homology domain, and is common to the 4 known isoforms. Western blot analysis showed an absence of full length and truncated protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations