Version: 8.0.0
Date: Tue Jan 28 2025
Jchaintm1Tl
MGI:2451101
Allele of Jchain
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Jchaintm1Tl

Species
Mus musculus
Symbol
Jchaintm1Tl
Category
allele
Allele of gene
Jchain
Transgenic Constructs
None
Synonyms
  • JDTA
Description
The gene was disrupted by replacement of exon 1 with a diphtheria toxin A (DTA) chain gene and a floxed neomycin resistance cassette. The exon 1 splice site is situated 3' to the neo cassette. The floxed neo cassette was removed by transient expression of cre recombinase in correctly targeted ES cells, thus allowing transcription from the DTA gene.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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