Allele/Variant

Apoa1tm2(APOA1)Prli

Species
Mus musculus
Symbol
Apoa1tm2(APOA1)Prli
Category
allele
Allele of gene
Apoa1
Transgenic Constructs
Synonyms
  • A-Im k-in
Description
Human APOA1 sequence carrying the milano missense mutation (R173C) which is associated with a reduced risk for cardiovascular disease was inserted into the endogenous locus via homologous recombination. Murine exons 2 through 3 were replaced with human exons 2 through 4, while murine exon 4 was disrupted by a neomycin selection cassette.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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