Allele/Variant

Gpx4tm1Prol

Species
Mus musculus
Symbol
Gpx4tm1Prol
Category
allele
Allele of gene
Gpx4
Transgenic Constructs
None
Synonyms
  • Gpx4-
Description
Exons 3 through 7 of the endogenous gene were replaced with an hprt cassette inserted by homologous recombination. Transcript and protein levels were reduced by approximately 50% relative to wild-type levels in heart, liver, kidney, brain, and testes tissues.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations