Allele/Variant

Pigrtm1Fejo

Species
Mus musculus
Symbol
Pigrtm1Fejo
Category
allele
Allele of gene
Pigr
Transgenic Constructs
None
Synonyms
  • pIgR-
Description
Exon 3, which encodes the ligand binding extracellular receptor domain 1 (D1), was disrupted by a neomycin selection cassette inserted by homologous recombination. Two aberrant transcripts were identified in homozygous mutant mice by Northern blot analysis. Both transcripts lacked sequence encoding the extracellular binding domain and were not expected to bind the endogenous ligand. This targeting vector was also electroporated into ES cells derived from a C57BL/6 background to generated Pigrtm1Rast.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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