Allele/Variant

Ptprjtm1Taka

Species
Mus musculus
Symbol
Ptprjtm1Taka
Category
allele
Allele of gene
Ptprj
Transgenic Constructs
None
Synonyms
  • CD148DeltaCyGFP
Description
A targeting vector designed to replace sequence encoding 117 carboxy terminal amino acids with sequence encoding EGFP and neo was inserted at the endogenous locus via homologous recombination. RT-PCR and Northern blot analyses confirmed the presence of fusion transcript in mutant mice. Western blot analysis showed the level of fusion protein to be approximately half of that of the wild-type protein, indicating reduced stability. GFP fluorescence was not detected in mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations