Tgfbr3^tm1Stv

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Species

Mus musculus

Symbol

Tgfbr3^tm1Stv

Category

allele

Allele of gene

Tgfbr3

Transgenic Constructs

None

Synonyms

• betaglycan^-
• TBRIII^-

Description

A PGK-Neo expression cassette was inserted in the "sense" orientation into exon 2. Homologous recombination was verified by Southern blot analysis. Two weak bands representing aberrent transcripts were seen in northern blots of mRNA from embryos homozygous from the targeted gene. RT-PCR analysis confirmed that none of these transcripts represented wild-type mRNA and affinity labelling of embryo fibroblasts with TGFbetaI indicated that there was no binding to TGFbetaRIII.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations