Version: 8.0.0
Date: Tue Jan 28 2025
Fcgr1tm1Jsv
MGI:2664927
Allele of Fcgr1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Fcgr1tm1Jsv

Species
Mus musculus
Symbol
Fcgr1tm1Jsv
Category
allele
Allele of gene
Fcgr1
Transgenic Constructs
None
Synonyms
  • FcgammaRI-
  • Fcgr1tm1Sjv
Description
The 3' part of the promoter, the exons encoding the L1 and L2 domains, and the 5' portion of the exon encoding the EC domain were deleted and replaced with a hygromycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of RNA from neutrophils, macrophages, and dendritic cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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