Allele/Variant

Cd81tm1Tmiy

Species
Mus musculus
Symbol
Cd81tm1Tmiy
Category
allele
Allele of gene
Cd81
Transgenic Constructs
None
Synonyms
  • CD81-
Description
Exons 3 through 7 and part of exon 8 (including the TGA stop codon) were replaced with a Neomycin resistance gene. These exons encode the second extracellular loop, the second through fourth membrane spanning domains and the entire C-terminal intracellular domain. Absence of gene expression was established by Northern blot analysis and RT-PCR and absence of protein was confirmed by cytofluorometric analysis of splenic B cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations