Version: 8.0.0
Date: Tue Jan 28 2025
Trpv4tm1Msz
MGI:2667379
Allele of Trpv4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Trpv4tm1Msz

Species
Mus musculus
Symbol
Trpv4tm1Msz
Category
allele
Allele of gene
Trpv4
Transgenic Constructs
None
Synonyms
  • Trpv4-
  • TRPV4KO
Description
A neomycin resistance gene was inserted into exon 4 which encodes the ankyrin-repeat domain. Transcripts were undetectable by RT-PCR and Northern blot in trigeminal root and dorsal root ganglia of homozygous animals. Immunohistochemical staining of the dorsal root ganglion confirmed the success of gene disruption.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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