Allele/Variant

Hip1tm1Hay

Species
Mus musculus
Symbol
Hip1tm1Hay
Category
allele
Allele of gene
Hip1
Transgenic Constructs
None
Synonyms
  • HIP1-
Description
Exon 8 was replaced with a cassette containing a splice acceptor site, an IRES, and sequence encoding a bifunctional lacZ-neomycin fusion protein. The insertion was designed to disrupt the expression of both isoforms that result from alternative splicing of the 5' region. Western blot analysis of the frontal cortex and striatum indicated an absence of normal protein in homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations