Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Gpamtm1Rcol
- Species
- Mus musculus
- Symbol
- Gpamtm1Rcol
- Category
- allele
- Allele of gene
- Gpam
- Transgenic Constructs
- None
- Synonyms
- Gpat1-
- mtGPAT-
- Description
- A 0.5 kb genomic fragment encoding 62 amino acids including those that make up homology regions II and III was replaced with a neo cassette inserted by homologous recombination. Transcript was undetected by Northern blot analysis of homozygous mutant liver tissue. Activity assays indicated a near comlpete ablation of endogenous activity and showed that the activity of the microsomal isoform was unperturbed.
- Additional Information
- Literature