Allele/Variant

Itga2btm1(GFP/cre)Emam

Species
Mus musculus
Symbol
Itga2btm1(GFP/cre)Emam
Category
allele
Allele of gene
Itga2b
Transgenic Constructs
Synonyms
  • gpIIb-
  • gpIIbGFPCre
Description
The endogenous locus was disrupted by homologous recombination of a targeting vector containing sequence encoding a GFP-cre fusion protein followed by an FRT-flanked PGK-neo cassette. While expression of cre recombinase was detected in (and limited to) the megakaryocyte lineage by Western blot analysis, GFP fluorescence was not observed. Endogenous protein was undetected by either flow cytometry or Western blot analysis of homozygous mutant bone marrow cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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