Allele/Variant

Runx1tm1Buch

Species
Mus musculus
Symbol
Runx1tm1Buch
Category
allele
Allele of gene
Runx1
Transgenic Constructs
None
Synonyms
  • AMLX
Description
A floxed neo cassette was inserted into intron 5, 1496 bp downstream of exon 5. This allele, in combination with allele Runx1t1tm1Buch in the same cells was used for the engineering of T(4;16), a reciporical translocation that replicates the human acute myeloid leukemia (AML) associated translocation, T(8;21).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations