Allele/Variant

Cd3gtm2Amk

Species
Mus musculus
Symbol
Cd3gtm2Amk
Category
allele
Allele of gene
Cd3g
Transgenic Constructs
None
Synonyms
  • CD3gamma-deltaITAM
  • CD3gammadeltaI
Description
A 3' portion of exon 5 and all of exon 6 were deleted by the incorporation of a targeting vector. The deleted region included sequence encoding the ITAM domain. While protein was undetected by immunoprecipitation, it was detected in homozygous mutant mice by SDS-PAGE, putatively because the anti-Cd3g serum recognizes epitopes present in the deleted region.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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