Allele/Variant

Entpd1tm1Djp

Species
Mus musculus
Symbol
Entpd1tm1Djp
Category
allele
Allele of gene
Entpd1
Transgenic Constructs
None
Synonyms
  • cd39-
Description
Sequence encompassing exons 5, 6, and 7 was replaced by PGK-neo inserted by homologous recombination. The deleted region encoded the enzymatically active extracellular portion of the mature protein that included apyrase-conserved regions 2 through 4. Although transcript 3' of the neo insertion was detected in homozygous mutant mice Northern blot analysis, apyrase activity and immunoreactivity were undetected.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations