Allele/Variant

Gas6tm1Pec

Species
Mus musculus
Symbol
Gas6tm1Pec
Category
allele
Allele of gene
Gas6
Transgenic Constructs
None
Synonyms
  • Gas6-
Description
Sequences encoding the transcription start site, the start codon, the signal peptide, and the Gla module which is required for binding of the endogenous protein to phospholipid membranes were deleted. Normal transcript was undetected by Northern blot analysis of MEFs derived from homozygous mutant mice, while normal protein was shown to be absent from homozygous mutant kidney extracts by Western blot analysis using an antibody directed against the C-terminal.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations