Allele/Variant

Pecam1tm1Mak

Species
Mus musculus
Symbol
Pecam1tm1Mak
Category
allele
Allele of gene
Pecam1
Transgenic Constructs
None
Synonyms
  • CD31-
  • CD31KO
Description
A neomycin selection cassette was inserted into exon 7 of the gene. No functional protein was expressed on the surface of PBLs as demonstrated by flow cytometry analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal cytokine secretion
MGI
abnormal leukocyte physiology
MGI
abnormal lung morphologyMGI
abnormal pulmonary alveolar sac morphologyMGI
decreased lung endothelial cell migrationMGI
glomerular capillary congestion
MGI
impaired lung alveolus developmentMGI
increased interferon-gamma secretion
MGI
increased pulmonary alveolus wall thicknessMGI
increased susceptibility to induced arthritisMGI
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Disease Associations

No data available