Allele/Variant

Ern2tm1Dron

Species
Mus musculus
Symbol
Ern2tm1Dron
Category
allele
Allele of gene
Ern2
Transgenic Constructs
None
Synonyms
  • IRE1beta -
Description
A neomycin selection cassette replaced 2.6 kb of genomic DNA that contains exons 12 and 13 which encode amino acid residues 408-497 in the transmembrane domain. Immunoprecipitation and western blot analysis demonstrated that no detectable protein is produced from this allele in colonic mucosa.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations