Version: 8.0.0
Date: Tue Jan 28 2025
Tg(ACTB-cre)1Tes
MGI:2677702Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(ACTB-cre)1Tes

Species
Mus musculus
Symbol
Tg(ACTB-cre)1Tes
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The sequence encoding cre recombinase was under the control of the human beta-actin promoter. This line differs from other beta-actin driven transgenes in that expression was driven during early embryogenesis in a stochastic manner. While uniform transgenic expression was detected in the testis, mosaic patterns of cre-mediated recombination were observed in various organs including the liver, heart, lung, pancreas, brain, retina, spleen, and adrenal gland.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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