Version: 8.0.0
Date: Tue Jan 28 2025
Cdkn2atm1Nesh
MGI:2677722
Allele of Cdkn2a
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cdkn2atm1Nesh

Species
Mus musculus
Symbol
Cdkn2atm1Nesh
Category
allele
Allele of gene
Cdkn2a
Transgenic Constructs
None
Synonyms
  • Arf-
  • P19ARF-
Description
A premature stop codon was generated in exon 1 beta, unique to P19ARF, by cre-mediated excision of a floxed neomycin cassette, leaving the cis-regulatory elements of both P19ARF and P16INK4 intact. Loss of P19ARF and presence of P16INK4 was confirmed by western blot analysis of homozygous mutant MEFs.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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